منابع مشابه
Muscle damage induced by black cohosh (Cimicifuga racemosa).
Extracts of black cohosh (Cimicifuga racemosa) are commonly used for the treatment of symptoms associated with menopause. Adverse events with black cohosh are rare, mild and reversible. A few number of serious adverse events, including hepatic and circulatory conditions, have been also reported, but without a clear causality relationship. We report the case of a woman with severe asthenia and v...
متن کاملTherapeutic efficacy and safety of Cimicifuga racemosa for gynecologic disorders.
The reproducible quality of phytopharmaceuticals--herbal medicines--is an essential prerequisite for good efficacy and tolerability in the treatment of functional disorders. In clinical trials and scientific investigations, standardized assessments (i.e., validated, internationally recognized and accepted scales) provide the basis for establishing clinical efficacy and tolerability. Extracts (e...
متن کاملIsolation of CYP3A4 Inhibitors from the Black Cohosh (Cimicifuga racemosa)
Recent investigation on drug interaction has shown that some foods and herbal medicines increase the oral availability of a variety of CYP3A4 substrates, which is caused by the reduction of CYP3A4 in intestinal epithelium. During the course of our investigation on CYP3A4 interaction, we found that the commercially available dietary supplement made from black cohosh (Cimicifuga racemosa) showed ...
متن کاملCimiracemoside a: A new cyclolanostanol xyloside from the rhizome of Cimicifuga racemosa.
A new 9,19-cyclolanostane-type triterpene xyloside (1), from the rhizomes of Cimicifuga racemosa, has been isolated together with four known saponins; cimiaceroside A, 25-O-methylcimigenol-3-O-beta-D-xylopyranoside, 27-deoxyactein and 23-O-acetylshengmanol-3-O-beta-D-xylopyranoside. The structure of the new compound was established as 16beta,23:22beta,25-diepoxy-12-acetoxy-3beta,23,24b eta-trih...
متن کاملA case of hepatitis associated with long-term use of Cimicifuga racemosa.
Cimicifuga racemosa and Hepatitis Alfredo Vannacci, MD, PhD, is a medical consultant at the Tuscan Regional Centre of Pharmacovigilance and a researcher in the Department of Preclinical and Clinical Pharmacology, Florence, Italy. Francesco Lapi, PharmD, PhD, is a research consultant at the Tuscan Regional Centre of Pharmacovigilance, a research fellow in the Department of Preclinical and Clinic...
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ژورنال
عنوان ژورنال: Journal of Natural & Ayurvedic Medicine
سال: 2018
ISSN: 2578-4986
DOI: 10.23880/jonam-16000148